姓名：谷小婷

职称：讲师

学科方向：药物代谢与药物动力学

研究方向：药物研发中的药代动力学

通讯地址：南开大学药学院天津市津南区海河教园同砚路38号300350

电子邮件：guxiaoting@nankai.edu.cn

教师简介：2012年至2016年就读于沈阳药科大学药学（基础药学理科基地班）专业，获得理学学士学位，同年保送研究生进入沈阳药科大学药学院并直接攻读药物分析博士学位，2021年获药物分析专业博士学位，同年7月入职南开大学药学院。主要研究方向为药物研发中的药物代谢与药物动力学，主持“天津市自然科学基金-青年项目”一项，发表文章九篇。

代表性论文：

1.Xiaoting Gu, Cuiting Wu, Mengmeng Zhang, Xin Wang, Youping Liu, Xin Di*. Rapid determination of seven bioactive components in rat plasma by UPLC-MS/MS and its application to pharmacokinetic compatibility study of Jinlingzi San[J]. Journal of Pharmaceutical and Biomedical Analysis, 2021.

2.Xiaoting Gu, Dongwu Wang, Xin Wang, Youping Liu, Xin Di*. Fast Screening of Biomembrane-Permeable Compounds in Herbal Medicines using Bubble-Generating Magnetic Liposomes coupled with LC–MS[J]. Molecules, 2021.

3.Ting Xiao#, Dandi Gao#, Xiaoting Gu#, Yuxin Zhu, Zihui Zhang, Yiming He, Luqing Wei, Hongli Li*, Honggang Zhou*, Cheng Yang*. Flavokawain A ameliorates pulmonary fibrosis by inhibiting TGF-β signaling pathway and CXCL12/CXCR4 axis[J]. Phytotherapy Research,2023.

4.Shanshan Chen, Dandi Gao, Ronghao Sun, Jiali Bao, Chunya Lu, Zihui Zhang, Ting Xiao*, Xiaoting Gu*, Honggang Zhou*. Anlotinib prove to be a potential therapy for the treatment of pulmonary fibrosis complicated with lung adenocarcinoma[J]. Pulmonary Pharmacology & Therapeutics, 2023.

5.Dongwu Wang, Xiaoting Gu, Kewang Fang, Buyun Fu, Youping Liu, Xin Di*. Study on quality control of Zuojin pill by HPLC fingerprint with quantitative analysis of multi-components by single maker method and antioxidant activity analysis[J]. Journal of Pharmaceutical and Biomedical Analysis, 2023.

6.Shaoyan Gao, Xiaohe Li, Qiuyan Jiang, Qing Liang, Fangxia Zhang, Shuangling Li, Ruiqin Zhang, Jiaoyan Luan, Jingyan Zhu, Xiaoting Gu, Ting Xiao, Hui Huang, Shanshan Chen, Wen Ning*, Guang Yang*, Cheng Yang*, Honggang Zhou*. PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling[J]. Science Advances, 2022.

7.Dongke Ma, Xiaoting Gu, Xin Wang, Youping Liu, Xin Di*. Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of Lycopodii Herba Extract by LC-MS/MS[J]. Molecules, 2019.

8.Chang Gao, Xiaoting Gu, Xin Wang, Huikun Cao, Bin Lin, Youping Liu, Xin Di*. Corygaline A, a hexahydrobenzophenanthridine alkaloid with an unusual carbon skeleton from Corydalis bungeana Turcz[J]. Organic & biomolecular chemistry, 2018.

9.陈莉，朱雨昕，李霄鹤，肖婷，谷小婷*，周红刚*.瘢痕疙瘩细胞和分子机制研究进展.中国药理学通报，2022.