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许婧

姓名:许婧

性别:

职称:研究员

学科方向:药物化学(天然药物化学);生药学

招生方向:天然药物化学;生药学


联系地址:南开大学药学院,天津市津南区海河教育园区同砚路38号,邮编300350

电子邮箱:xujing611@nankai.edu.cn


教师简介:

许婧,女,研究员。2007年6月毕业于沈阳药科大学天然药物化学专业,获得博士学位。2007年7月进入南开大学工作。2009年晋升为副教授,2014年晋升为研究员。2017.10-2018.10,美国加州大学洛杉矶分校(UCLA)访问学者。负责本科生《天然药物化学》实验课程,以及研究生《现代分离技术》等课程。

研究方向:天然药物化学;生药学

主要从事中药和天然药物中生物活性成分(包括小分子次生代谢产物及大分子多糖)的研究;中药药效物质基础研究;天然药物及中药抗AD及抗肿瘤作用机制研究,及其相关的新药及功能食品的研究与开发。先后主持国家自然科学基金3项,天津市自然科学基金1项,参与国家自然科学重点项目、天津市自然科学基金重点项目等多项。作为第一作者或通讯作者,在Journal of Natural Products,Carbohydrate Polymers,Phytochemistry,Food Chemistry,International Journal of Biological Macromolecules等国际期刊发表SCI论文80余篇,申请发明专利10余项。

代表性论文:

1) Huimei Wang, Xuelian Wang, Ying Li, Shaojie Zhang, Zhengguo Li, Yuhao Li, Jianlin Cui, Xiaozhong Lan, Erhao Zhang, Lei Yuan, Da-Qing Jin, Muhetaer Tuerhong, Munira Abudukeremu, Jing Xu*, Yuanqiang Guo*, Structural properties and in vitro and in vivo immunomodulatory activity of an arabinofuranan from the fruits of Akebia quinata, Carbohydrate Polymers, 2021, 256, 117521.

2) Shaojie Zhang, Qi Zhang, Lijun An, Jiaojiao Zhang, Zhengguo Li, Jie Zhang, Yuhao Li, Muhetaer Tuerhong, Yasushi Ohizumi, Jin Jin, Jing Xu*, Yuanqiang Guo*, A fructan from Anemarrhena asphodeloides Bunge showing neuroprotective and immunoregulatory effects, Carbohydrate Polymers, 2020, 229: 115477.

3) Zhaoyu Shi, Lijun An, Shaojie Zhang, Zhengguo Li, Yuhao Li, Jianlin Cui, Jie Zhang, Da-Qing Jin, Muhetaer Tuerhong, Munira Abudukeremu, Jing Xu*, Yuanqiang Guo*, A heteropolysaccharide purified from leaves of Ilex latifolia displaying immunomodulatory activity in vitro and in vivo, Carbohydrate Polymers, 2020, 245: 116469.

4) Jiaojiao Zhang, Zhengguo Li, Linan Zhou, Jiahe Bao, Jing Xu*, The modifications of a fructan from Anemarrhena asphodeloides Bunge and their antioxidant activities, International Journal of Biological Macromolecules, 2020, 164: 4435–4443.

5) Min Du, Lijun An, Jing Xu*, Yuanqiang Guo*, Euphnerins A and B, Diterpenoids with a 5/6/6 Rearranged Spirocyclic Carbon Skeleton from the Stems of Euphorbia neriifolia, J. Nat. Prod., 2020, 83, 2592−2596.

6) Honghong Xing, Lijun An, Ziteng Song, Shanshan Li, Huimei Wang, Chunyan Wang, Jie Zhang, Muhetaer Tuerhong, Munira Abudukeremu, Dihua Li, Dongho Lee, Jing Xu*, Namrita Lall, Yuanqiang Guo*, Anti-Inflammatory ent-Kaurane Diterpenoids from Isodon serra, J. Nat. Prod., 2020, 83, 2844−2853.

7) Bangjian Dong#, Xueyuan Yang#, Wenpei Liu, Lijun An, Xuke Zhang, Muhetaer Tuerhong, Qing Du, Chunyan Wang, Munira Abudukeremu, Jing Xu*, Dongho Lee, Ling Shuai, Namrita Lall, Yuanqiang Guo*, Anti-inflammatory neo-clerodane diterpenoids from Ajuga pantantha, J Nat Prod., 2020, 83(4): 894-904.

8) Feng Liu#, Jun Ma#, Zhaoyu Shi#, Qi Zhang#, Huimei Wang, Dihua Li, Zhaohui Song, Chunyan Wang, Jin Jin, Jing Xu*, Muhetaer Tuerhong, Munira Abudukeremu, Ling Shuai, Dongho Lee, Yuanqiang Guo*, Clerodane diterpenoids isolated from the leaves of Casearia graveolens, J. Nat. Prod., 2020, 83(1): 36-44.

9) Yue Liang, Lijun An, Zhaoyu Shi, Xuke Zhang, Chunfeng Xie, Muhetaer Tuerhong, Zhaohui Song, Yasushi Ohizumi, Dongho Lee, Ling Shuai, Jing Xu*, Yuanqiang Guo*, Bioactive diterpenoids from the stems of Euphorbia antiquorum, J. Nat. Prod., 2019, 82(6): 1634−1644.

10) Peixia Wang, Chunfeng Xie, Lijun An, Xueyuan Yang, Yaru Xi, Shuo Yuan, Chenyue Zhang, Muhetaer Tuerhong, Da-Qing Jin, Dongho Lee, Jie Zhang, Yasushi Ohizumi, Jing Xu*, Yuanqiang Guo*, Bioactive diterpenoids from the stems of Euphorbia royleana, J. Nat. Prod., 2019, 82(2): 183−193.



 


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