FacultyProfessor
Bing Q. Shen

Dr. Bing Q. Shen, Professor

Research Interests: Cell culture engineering, cell therapeutics, drug delivery nanosystems

Email: bqshen@nankai.edu.cn

Address: College of Pharmacy, Nankai University, 38 Tongyan Road, Tianjin, China 300350

Prof. Shen obtained his Ph.D. in Chemical Engineering from the University of Queensland in 1991, studying protein-free cultivation of hybridomas in novel bioreactors. His postdoctoral training at the University of Michigan involved the process development of retroviral vector production for gene therapy and hematopoietic stem cell bioreactor design. From 1993 Prof. Shen, as a group leader and research scientist, was in charge of various industrial R&D projects including protein expression processes, embryonic stem cell expansion and differentiation, cellular models for drug screening, and delivery systems for cells and biomolecules, during his employment with three US companies including Monsanto Co. Prof. Shen was a Principle Investigator at Shanghai Institutes for Biosciences and Professor of Graduate School, Chinese Academy of Sciences prior to his affiliation with Nankai in 2008. Prof. holds a B.S. in Biochemistry from East China University of Science & Technology (1984) and M.Sc. in Biotechnology from the University of New South Wales (1987).

Representative publications:

1.  Xianghui Gong, Qiangyi Fang, Xuesen Li, Xiangzong Han, Yuyin Wu, Shengli Yang, Bing Q. Shen* (2005). A high-throughput end-point assay for viable mammalian cells, Cytotechnology 49: 51-58;

2.  Xianghui Gong, Dongxiao Li, Xiangzong Han, Qiangyi Fang, Yuyin Wu, Shengli Yang, Bing Q. Shen* (2006). Fed-batch culture optimization of a growth-associated hybridoma cell line, Cytotechnology 52: 25-38;

3.  Xiangzong Han, Lei Sun, Dongxiao Li, Qiangyi Fang, Shengli Yang, Bing Q. Shen* (2007). Transient expression of osteopontin in HEK 293 cells in serum-free culture, Enzyme & Microbial Technology 41: 133-140;

4. Xiangzong Han, Qiangyi Fang, Feng Yao, Xiaoning Wang, Jufang Wang, Shengli Yang, Bing Q. Shen* (2009). The heterogeneous nature of polyethylenimine-DNA complex formation for transient gene expression, Cytotechnology 60:63-75;

5.  Qiangyi Fang, Bing Q. Shen* (2010) Optimization of polyethylenimine-mediated transient transfection using response surface methodology design, Electronic Journal of Biotechnology, 13(5):1-11.

Patent Granted:

Composition and method for preparing alginate nanocapsules, US Patent 8,449,919


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